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Reached a new U.S. study to another option for patients with acute lymphoblastic leukemia than children who did not respond to initial chemotherapy, and that subjecting them to additional course of chemotherapy, a type of treatment, more focused, rather than undergo a bone marrow transplant.Disease and acute lymphoblastic leukemia, or what is known as Acute lymphoblastic leukemia (ALL) is a cancer that affects the blood and bone marrow.
Says study author Bo Cheng Hoon that the failure to achieve improvement after undergoing chemotherapy prompter "induction therapy", is rare, as it happens with 2 to 3% of sick children with (ALL). But when that happens, these children are bad results, making them candidates for bone marrow transplant option for them.
He said Poe, a head of cancer treatment hospital, St Jude Research Children in Memphis, U.S., that "some patients and their parents may feel good when they know that the bone marrow transplant is not an option the only remaining to them. But can they are subject to additional doses of chemotherapy."
In this study, recently published in the newspaper "New England," for Medicine, the researchers follow more than 1000 sick child leukemia type of ALL who did not score for the remission of the disease have yet to undergo four to six weeks of chemotherapy.
These children were diagnosed for the first time when they were small at ages ranging between one and five years.
The rate of overall survival for children who did not register the case of remission of the disease after undergoing chemotherapy center 32%.
However, the rate reached 72% among a group of children who have undergone additional doses of chemotherapy instead of giving in to the bone marrow transplant.
The researchers say that this kind of patients have some kind of disease that begins in ALL cells, white blood cells, and then turns into B cells (B-lineage ALL).
These patients represent approximately 25% of the sample individuals who did not happen to have a remission of the disease after the treatment center, and patients who do not respond to treatment prompter probably do not need a bone marrow transplant are patients who have a cell B-cell.
And the rest of the patients who are not making progress with the treatment center should undergo marrow transplant as the best treatment available to them.
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