New hope for cancer patients

The new test provides a more effective treatment in weeks (French)

U.S. doctors developed a new method to test patients with a wide range of genetic variants at the same time, which allows them to make treatment more effective and targeted in a matter of weeks.

I have been using the new test, called the "Snabashot" to identify mutations in more than fifty places in 14 major gene in patients with a form of lung cancer the most commoncancer known as non-small cell lung and is provided now for patients with a range of other cancers.

It is noteworthy that the analysis of the genetic makeup of cancers is becoming more common, but usually what happens to a certain single-gene mutations and then believethat this is the first time that the use of such large-scale clinical testing.

She told Isshiah Squist - who led the research at Massachusetts General Hospital in Boston - that this study are interesting because they demonstrate the possibility of merging the genetic testing of multiple biomarkers in the clinic of any active and guide patients toward personalized treatments.
The method used Squist PCR, a method based on the generation of multiple copies of part of the DNA, which is usually during the heating and cooling cycles, to provide more material for testing.
Has used this formula developed, known as polymerase chain reaction of multiple laboratories in the criminal several years ago to target multiple genes simultaneously. The recent proliferation of new cancer drugs that target certain cancers, genetic defects lead to increased demand for such tests.
Among the 589 cancer patients non-small cell lung who were tested were 546 biopsy samples of tissue contained enough tissue to generate results. Found in more than half, 51%, mutation or more of the genes of cancer or some kind of defect, called a translocation, which is part of the integrated DNA in the chromosome error.
Of the 353 people living with advanced and found mutations in 170 of them or Mratbaat potential treatments can be targeted. These patients can be enrolled in clinical trials of drugs that target the specific genetic makeup of their illness.
It is worth mentioning that the test - which costs about $ 498 - provided through 14 hospitals and clinics specializing in lung cancer across the United States.
The Squist Choosing the correct treatment can increase response rates in patients with lung cancer non-small cell of about 20% - 30% to 60% - 75% may improve chances of survival.


Source: Guardian

Beginning of the end of malaria

New discovery completely eradicated malaria (French)
The discovery of a new British scientists turn the balance of the war against the most deadly global disease, namely malaria.
It was announced and scientists at the Wellcome Trust Sanger in Cambridge on Wednesday on the progress of large may be more important than the news reported a month ago for the experimental vaccine created the British pharmaceutical company Glaxo Smith Kline, which showed partially successful in early clinical trials. The Scientists at the trials that the vaccine will contribute only to the reduction of malaria.
But the discovery of Cambridge scientists provides a glimmer of hope is not a huge total eradication of the disease globally. This goal is interesting and has become much closer, thanks to the discovery of the crucial element in the human red blood cells, which appears to be vital for the parasite to complete its life cycle inside the human body. In fact, were identified weakness in this deadly parasite. This means the possibility of designing a vaccine to prevent the development of the parasite within the infected person and thus protect against the disease and the mosquito vectors to him.
It is well known that malaria is one of the most deadly childhood diseases in the world. The estimated number of people who die each year are affected about one million, mostly children under five living in sub-Saharan Africa.
Dr. Julian Rainer Sanger Institute, the interaction "between the malaria parasite and red blood cells, which we found has the potential to be the basis of the vaccine could save millions of people."
The focus of the work behind the big reveal on the second phase of the life cycle of malaria in the human body, after he leaves the liver to invade red blood cells during the phase of what is known as "Aloksoma."
Institute scientists were able to identify a human protein called "Basegin" on the outer membrane of red blood cells of man who seems to be needed to open the parasite membrane and the invasion of the cell.
Dr. Renner "The malaria parasite travels between mosquitoes and humans back and forth. But the stage that cause actual symptoms of the disease is when the invading parasite of red blood cells of man. It must enter the red blood cell to divide and spread and multiply, and this is essential for the survival of the parasite. But also a potential target for attack. "
Once the scientists identified the protein main "future" on the red cell membrane devised a test to see if it is possible to prevent interaction between the malaria parasite and the cell.They succeeded by using antibodies designed to replicate the future adhesion protein on the parasite and thus prevents the parasite from the use of the key that opens the lock by the red cells.
For his part, said Professor Adrian Hill of the Jenner Institute, Oxford This is the great progress that can improve future vaccines. He added that reports positive results from tests developed in Africa, encouraging, and discover the future one can hope to give the target a much more effective solutions.


Source: Independen

The bombing of a new gas pipeline in Egypt

Tongues of flame rising from the site prior to the bombing of the Egyptian gas pipeline (French)
Egyptian security forces announced that the tube that carries Egyptian gas to Israel and Jordan was attacked again in the early hours of Thursday, for the seventh time since February last year.
Quoted by Agence France-Presse quoted a security source said the blast occurred about 60 km from the city of El-Arish, North Sinai peninsula. The source said that witnesses had seen armed men in the place, but could not say whether there were any casualties.
The flames were seen rising to great heights, and headed for fire trucks and ambulance to the place of the bombing of the gas pipeline, as I moved a large force of police, military and security leaders in the Sinai to the site, and authorities are conducting preliminary investigations to determine the circumstances of the bombing.
And deliver the export of Egyptian gas to Israel's opposition in Egypt for years. Opponents say that Egypt is the gas exported to Israel for less than market price, a price fixed in the contract will continue for many years.
They also said that the ousted government of President Hosni Mubarak violated legal procedures in the contract which is to offer the contract to the Council of People's Assembly (Parliament) for discussion and ratification or amendment.
After the fall of Mubarak in a popular revolution in February transmit to the Minister of PetroleumAnd Mineral Resources Sameh Fahmi, the former and six of the leaders of energy in Egypt to the Criminal Court on charges of causing the loss of the country hundreds of millions of dollars because of the contract. Is under Mubarak and businessman Hussein Salem, close to him, who fled to Spain for the same charge along with other charges.
Egypt was announced last month that pumping natural gas across the line afterRepair the damage it suffered in the previous explosion.
This tube and subjected to six attacks since February last, which led to a cessation of pumping gas to Israel and Jordan. And also foiled several attacks in recent months.
The attack comes despite the heavily guarded by the army and police, and the development of early warning gas stations that were destroyed before.
The Egyptian authorities announced several times for procedures to enhance the protection of these facilities and tried to arrest the perpetrators of these attacks.

Source: Agencies

Volcanic ash benefit scientists climate history

Image via Wikipedia



Could help scientists in the volcanic ash tracking the historical changes of climate in the past through the study of solid particles in it.

 

The Swedish researcher said on Wednesday that although the ash confuse the movement of air travel, as happened when the revolution of volcanic Iceland and Chile, could help scientists in their studies on the historical climate change.


She Iowa researcher Linda from Stockholm University in the Ph.D. thesis focused on the North Atlantic that "studies on the historical climate changes in the past to study theglaciers or sediment, as it represents a record of changes in climatic conditions."

 

She said, however, that "the study of how the scattering of solid particles in the volcanic ash on the ground and the sea that can help scientists track climate change and its history", and he studied sediments and volcanic history researchers can developschedules and compare different data.

 

She noted that this method can be used in the study of rapid climate change that has occurred after the transition from the last ice ages, and even what is known as the Holocene era, a geological period dating back to between 13 thousand and 9 thousand years BC.
 

Source: German Press Agency

Describe the lessons of American Islam Baniv

U.S. Attorney General Eric Holder (Reuters)


The Minister of Justice, U.S. Eric Holder expressed his displeasure about the courses offered to the staff of the Federal Police, which describes Islam as "a very violent religion" and is a qualified American Muslims to sympathize with "terrorism."


Holder emphasized that these lessons will never be a part of the education program, adding that American Muslims are "essential partners in addressing terrorism" and are trusted sources of information that allowed the achievement of a large number of successes, as he put it.


At a hearing in the Senate, said the U.S. official said that the courses offered would hit efforts may lead to negative consequences in communication with American Muslims.


The Holder is contained in his speech to the Democratic Senator Dick Durban, who pointed out that the documents of the Federal Police recently published show that the agency launched a campaign of widespread surveillance targeting mosques and Muslim American is accused of any misdemeanor.


The Wired Magazine revealed in September / September last for the existence of such lessons introduced by an expert in the fight against "terrorism" and called William Gautrob which is that Islam itself is not dangerous and al-Qaeda.


The Minister of Justice announced that Gautrob is no longer an employee of the Federal Police.


 Source: French

Confirm the imprisonment of the former President of Israel

Israeli Supreme Court upheld an earlier prison Katsav seven years (French)
Israeli Supreme Court said Thursday that the former President of Israel Moshe Katsav raped his former assistant, molested two women two, and upheld the sentence, who was earlier this year sentenced to seven years.
She said the court - made up of three judges - in a Judgement unanimously rejected an appeal by Katsav, the former president "abused the high office which he held, and insulted the bodies and dignity of the owners claim," and ordered him to court to surrender to begin implementation of a prison sentence as of the seventh of December / December.
He served Katsav, 65, head of Israel in the period between 2000 and 2007 and was convicted in December / December of last year of raping a help to him twice while he was Minister the late nineties, was also convicted of harassment and sexual harassment of two had worked with him during his presidency of Israel.
A lawyer for the prosecution Naomi Jeranot after the verdict, "the Supreme Court decision reaffirms that everyone in Israel, both before the law."
Katsav has denied the charges against him repeatedly, but the court said that his version of events "can not be trusted to a great extent." The court in its ruling that Katsav "fell from the towering peaks of the abyss," she said "It's hard to see someone was a symbol of the state officially goes to prison."
The Israeli Parliament (Knesset), Katsav was elected president in 2000, achieving a surprise win over rival Shimon Peres winning the Nobel Peace Prize is the oldest men in the state of Israel, and behind Peres, Katsav then in office.
Despite the scandal that forced Katsav to step down in humiliation, the resignation did not have a significant impact on the work of the government because the presidency in Israel as a largely ceremonial.
And welcomed the President of the Labour Party Chile Yachimovich called as a witness by the prosecution of the court's decision, saying that "justice was served."
He criticized the lawyer Avigdor Feldman, Katsav told reporters after the trial, "the sentence of 11 years after the incident on the basis of dubious evidence."

Source: Agencies